Non-model model organisms

James J Russell; Julie A Theriot; Pranidhi Sood; Wallace F Marshall; Laura F Landweber; Lillian Fritz-Laylin; Jessica K Polka; Snezhana Oliferenko; Therese Gerbich; Amy Gladfelter; James Umen; Magdalena Bezanilla; Madeline A Lancaster; Shuonan He; Matthew C Gibson; Bob Goldstein; Elly M Tanaka; Chi-Kuo Hu; Anne Brunet

doi:10.1186/s12915-017-0391-5

Non-model model organisms

BMC Biol. 2017 Jun 29;15(1):55. doi: 10.1186/s12915-017-0391-5.

Authors

James J Russell¹, Julie A Theriot², Pranidhi Sood³, Wallace F Marshall⁴, Laura F Landweber⁵, Lillian Fritz-Laylin⁶, Jessica K Polka⁷, Snezhana Oliferenko^{8

9}, Therese Gerbich¹⁰, Amy Gladfelter¹⁰, James Umen¹¹, Magdalena Bezanilla⁶, Madeline A Lancaster¹², Shuonan He¹³, Matthew C Gibson^{13

14}, Bob Goldstein¹⁵, Elly M Tanaka¹⁶, Chi-Kuo Hu¹⁷, Anne Brunet^{17

18}

Affiliations

¹ Department of Biology, Howard Hughes Medical Institute Stanford University, Stanford, CA, 94305, USA.
² Departments of Biochemistry and of Microbiology & Immunology, Howard Hughes Medical Institute Stanford University, Stanford, CA, 94305, USA. theriot@stanford.edu.
³ Department of Biochemistry & Biophysics, University of California San Francisco, 600 16th St, San Francisco, CA, 94158, USA.
⁴ Department of Biochemistry & Biophysics, University of California San Francisco, 600 16th St, San Francisco, CA, 94158, USA. Wallace.marshall@ucsf.edu.
⁵ Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY, 10032, USA.
⁶ Department of Biology, University of Massachusetts, Amherst, MA, 01003, USA.
⁷ Visiting Scholar, Whitehead Institute, 9 Cambridge Center, Cambridge, MA, 02142, USA.
⁸ The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
⁹ Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.
¹⁰ 516 Fordham Hall, University of North Carolina Chapel Hill, Chapel Hill, NC, 27514, USA.
¹¹ Donald Danforth Plant Science Center, 975 N. Warson Rd, St. Louis, MO, 63132, USA.
¹² MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, CB2 0QH, Cambridge, UK.
¹³ Stowers Institute for Medical Research, Kansas City, MO, 64110, USA.
¹⁴ Department of Anatomy and Cell Biology, The University of Kansas School of Medicine, Kansas City, KS, 66160, USA.
¹⁵ Biology Department, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
¹⁶ Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus Vienna Biocenter 1, 1030, Vienna, Austria.
¹⁷ Department of Genetics, Stanford University, Stanford, CA, 94305, USA.
¹⁸ Glenn Laboratories for the Biology of Aging at Stanford, Stanford, CA, 94305, USA.

Abstract

Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems. This Forum highlights a range of 'non-model model organisms' as emerging systems for tackling questions across the whole spectrum of biology (and beyond), the opportunities and challenges, and the outlook for the future.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biology*
Eukaryota*
Models, Animal*
Plants

Abstract

Publication types

MeSH terms

Grants and funding