Does a glass of Coke boost the exposure to imatinib in gastrointestinal stromal tumour patients after gastrectomy?

Br J Clin Pharmacol. 2017 Oct;83(10):2312-2314. doi: 10.1111/bcp.13333. Epub 2017 Jul 4.
No abstract available

Keywords: acidic beverage; imatinib; major gastrectomy; pharmacokinetics.

Publication types

  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / pharmacokinetics
  • Carbonated Beverages*
  • Cross-Over Studies
  • Food-Drug Interactions
  • Gastrectomy / methods
  • Gastrointestinal Neoplasms / pathology
  • Gastrointestinal Neoplasms / therapy*
  • Gastrointestinal Stromal Tumors / pathology
  • Gastrointestinal Stromal Tumors / therapy*
  • Humans
  • Imatinib Mesylate / administration & dosage*
  • Imatinib Mesylate / pharmacokinetics

Substances

  • Antineoplastic Agents
  • Imatinib Mesylate