Preoperative breast radiation therapy: Indications and perspectives

Abstract

Preoperative breast radiation therapy (RT) is not a new concept, but older studies failed to change practice. More recently, there has been interest in revisiting preoperative RT using modern techniques. This current perspective discusses the indications, summarises the published literature and then highlights current clinical trials, with particular attention to combining with novel drugs and optimising associated translational research.

Keywords: IMRT; Preoperative breast radiation therapy; Translational research.