Full-length sequencing of the HLA region identified a novel allele, HLA-B*52:70

HLA. 2017 Oct;90(4):253-254. doi: 10.1111/tan.13089. Epub 2017 Jul 20.

Abstract

One nucleotide substitution at position 276 of HLA-B*52:01:01 results in a novel allele, HLA-B*52:70.

Keywords: HLA; HLA-B*52:70; novel allele.

MeSH terms

  • Alleles*
  • Amino Acid Substitution
  • Asian People
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • Gene Expression
  • Genotype
  • HLA-B52 Antigen / genetics*
  • HLA-B52 Antigen / immunology
  • Hematopoietic Stem Cell Transplantation
  • Histocompatibility Testing
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Tissue Donors*

Substances

  • Codon
  • HLA-B52 Antigen