Data privacy management and data quality monitoring in the German Centre for Cardiovascular Research's multicentre TranslatiOnal Registry for CardiomyopatHies (DZHK-TORCH)

ESC Heart Fail. 2017 Nov;4(4):440-447. doi: 10.1002/ehf2.12168. Epub 2017 Jul 18.

Abstract

Aims: The multicentric TranslatiOnal Registry for CardiomyopatHies (TORCH) of the German Centre for Cardiovascular Research aims to recruit 2300 patients with non-ischemic cardiomyopthies.

Methods and results: The investigations were performed after standard operating procedures. The data are collected in standardized electronic case report forms provided by the data holding of the central data management of the German Centre for Cardiovascular Research using secuTrial (interActive Systems GmbH, Berlin, Germany). The personal-identifying data and informed consent are collected, stored, and quality-checked by the independent Trusted Third Party in Greifswald. The quality management of the medical data is performed by the data and quality centre Greifswald. In December 2014, the recruitment for TORCH has started. Currently, data and biomaterial from about 1397 patients and more than 74 500 biomaterial aliquots were collected. Regular study centre-specific quality reports address completeness and plausibility of data and provide detailed information about current missing or implausible data entries to improve the data quality by using a query management in addition.

Conclusions: A regular quality control and reporting improve the data quality in TORCH and will support high-quality data analysis and the translation of research results into routine care.

Keywords: Cardiomyopathy; Central data management; Quality management; Registry.

Publication types

  • Multicenter Study

MeSH terms

  • Cardiomyopathies / epidemiology*
  • Data Accuracy*
  • Female
  • Germany / epidemiology
  • Humans
  • Informed Consent / standards*
  • Knowledge Management / standards*
  • Male
  • Middle Aged
  • Morbidity / trends
  • Privacy*
  • Registries / standards*
  • Translational Research, Biomedical / standards*