Emergencies and outcome in invasive out-of-hospital ventilation: An observational study over a 1-year period

Clin Respir J. 2018 Apr;12(4):1447-1453. doi: 10.1111/crj.12681. Epub 2017 Aug 16.

Abstract

Objectives: The number of ventilated patients is further increasing which leads to an increasing number of patients with weaning failure. In Germany, the treatment of patients with invasive out-of-hospital becomes more and more common. The aim of the study was to observe the outcome, the frequency and character of emergencies of patients with invasive out-of-hospital ventilation.

Methods: We conducted a prospective study over 1 year. Fifty-nine invasively ventilated patients living either at home or at nursing homes specialized in ventilator medicine were included.

Results: Forty-one (71%) of the patients were living in a nursing home. Chronic obstructive pulmonary disease (COPD) was the most common underlying disease (52.5%). Duration of daily ventilation did not change over the 1-year period. 52.8% of the months went without a documented emergency. The most common emergencies were oxygen desaturation (29.6%), increase of secretion (12.2%) and dyspnea (8.7%). We found no difference in the frequency of emergencies between patients cared for in their own home compared with residential care. Ten patients died during the observation period. Fewer emergencies (P = .02, CI 0.03-0.85) was the only parameter associated with a reduced mortality. Frequency of emergencies as well as survival showed no difference regarding the way patients were cared for.

Conclusions: In patients with invasive home mechanical ventilation survival for more than 1 year seems to be common. Only the rate of emergencies affected survival.

Keywords: COPD; high-technology home care; long-term ventilation; neuromuscular disorder; out-of-hospital ventilation; safety; ventilator-dependency; weaning failure.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Emergencies*
  • Emergency Medical Services / methods*
  • Female
  • Follow-Up Studies
  • Germany / epidemiology
  • Humans
  • Incidence
  • Male
  • Prospective Studies
  • Respiration, Artificial / methods*
  • Respiratory Insufficiency / epidemiology
  • Respiratory Insufficiency / therapy*
  • Survival Rate / trends
  • Time Factors
  • Treatment Outcome