Comparison of Clinical Data and Scores of Quality of Life, Anxiety, and Depression in Patients With Different Types of Intraductal Papillary Mucinous Neoplasms: A Prospective Study

Pancreas. 2017 Sep;46(8):1029-1034. doi: 10.1097/MPA.0000000000000890.

Abstract

Objectives: This study aims to evaluate the well-being of patients with main duct intraductal papillary mucinous neoplasms (MD-IPMNs) or mixed type IPMNs (mixed-IPMNs) of the pancreas.

Methods: Twenty-two patients with MD/mixed-IPMNs of the pancreas were studied, and an equal number of patients having branch duct IPMNs (BD-IPMNs) were used as controls. The short form (SF) -12 Health Survey, State Trait Anxiety Inventory Y-1 and Y-2, General Health Questionnaire, and Beck Depression Inventory II were used to evaluate the quality of life once a year for 2 consecutive years.

Results: At basal evaluation, the SF-12 Health Survey questionnaire administered to the 44 patients showed that the values of the physical component and mental component scores were similar between the 2 groups of patients studied. The State Trait Anxiety Inventory Y-1 and Y-2, General Health Questionnaire, and Beck Depression Inventory II scores were also similar in the 2 groups at basal evaluation. No differences were found between MD/mixed-IPMNs and BD-IPMNs at the 1-year and the 2-year evaluations.

Conclusions: The well-being of patients with MD/mixed-IPMNs did not differ as compared with patients with BD-IPMNs.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Adenocarcinoma, Mucinous / pathology
  • Adenocarcinoma, Mucinous / psychology*
  • Adenocarcinoma, Papillary / pathology
  • Adenocarcinoma, Papillary / psychology*
  • Adult
  • Aged
  • Aged, 80 and over
  • Anxiety / prevention & control*
  • Carcinoma, Pancreatic Ductal / pathology
  • Carcinoma, Pancreatic Ductal / psychology*
  • Depression / psychology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / psychology*
  • Prospective Studies
  • Quality of Life / psychology*
  • Surveys and Questionnaires