Data on the impact of the blood sample collection methods on blood protein profiling studies

Maria Ilies; Cristina Adela Iuga; Felicia Loghin; Vishnu Mukund Dhople; Thomas Thiele; Uwe Völker; Elke Hammer

doi:10.1016/j.dib.2017.07.025

Data on the impact of the blood sample collection methods on blood protein profiling studies

Data Brief. 2017 Jul 14:14:313-319. doi: 10.1016/j.dib.2017.07.025. eCollection 2017 Oct.

Authors

Maria Ilies^{1

2}, Cristina Adela Iuga^{1

3}, Felicia Loghin⁴, Vishnu Mukund Dhople², Thomas Thiele⁵, Uwe Völker^{2

6}, Elke Hammer^{2

6}

Affiliations

¹ Department of Pharmaceutical Analysis, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, no. 6 Louis Pasteur st., 400349 Cluj-Napoca, Romania.
² Department of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, F.-L.-Jahn-Str. 15a, 17475 Greifswald, Germany.
³ Department of Proteomics and Metabolomics, MedFuture Research Center for Advanced Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, no. 4-6 Louis Pasteur st., 400349 Cluj-Napoca, Romania.
⁴ Department of Toxicology, Faculty of Pharmacy Iuliu Hațieganu University of Medicine and Pharmacy, no. 6 Louis Pasteur st., 400349 Cluj-Napoca, Romania.
⁵ Institute of Immunology and Transfusion Medicine, University Medicine Greifswald, Sauerbruchstr., 17475 Greifswald, Germany.
⁶ DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.

Abstract

Complete blood protein profiles of 4 different blood sample collection methods (EDTA-, heparin- and citrate plasma and serum) were investigated and the data presented herein is an extension of the research article in Ilies et al. [1]. Specimens were depleted of 6 highly abundant proteins and protein profiling was assessed by nano-LC UDMS^E. Exhaustive protein sets and protein abundances before and after depletion are presented in tables and figures. Also, the core protein set and the unique proteins for each sample collection method previously described [1] are disclosed.

Keywords: LC-MSE method data; Plasma; Proteomics; Serum.