Association between modifiable lifestyle and the prevalence of atrial fibrillation in a Chinese population: Based on the cardiovascular health score

Clin Cardiol. 2017 Nov;40(11):1061-1067. doi: 10.1002/clc.22771. Epub 2017 Aug 21.

Abstract

Background: The Cardiovascular Health (CVH) Score was comprised of a series of modifiable lifestyle and health factors, which was published by American Heart Association in 2010. Its relationship with atrial fibrillation (AF) remains unclear.

Hypothesis: Individuals with a higher CVH Score had a lower risk of AF.

Methods: Participants ≥40 years of age were recruited from the Jidong community. Information regarding the following 7 CVH metrics, including smoking, body mass index, diet, physical activity, total cholesterol, and fasting blood glucose, were collected. AF was confirmed with a standard 12-lead electrocardiography or based on the patients' medical histories. A multivariable logistic regression model was used to evaluate the relationship between ideal CVH and AF prevalence.

Results: This study included 4477 individuals, among whom 48 had AF (1.07%). Overall, participants with higher ideal components scores had a lower risk of AF (odds ratio [OR]: 0.78; 95% confidence intervals [CI]: 0.62-0.97; P trend = 0.024). Subgroup analyses showed that the trend was consistent in the male participants ages 40 to 60 years. Moreover, patients with 5 to 7 ideal components or 3 to 4 ideal components were associated with 57% and 59% reduced risks for AF, respectively. We also detected a significant association between ideal health factors and the prevalence of AF (OR: 0.79; 95% CI: 0.68-0.93; P = 0.004).

Conclusions: Ideal health behavior and factors are associated with lower prevalence of AF in a community-based population. Improving healthy behavior and these factors may be beneficial to decrease the prevalence of AF.

Keywords: Atrial Fibrillation; Cardiovascular Health; Cross-Sectional Study.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / epidemiology*
  • Atrial Fibrillation / prevention & control
  • Biomarkers / blood
  • Blood Glucose / analysis
  • Blood Pressure
  • Body Mass Index
  • Chi-Square Distribution
  • China / epidemiology
  • Cholesterol / blood
  • Cross-Sectional Studies
  • Diet / adverse effects
  • Exercise
  • Female
  • Health Status
  • Health Surveys
  • Healthy Lifestyle
  • Humans
  • Life Style*
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Prevalence
  • Protective Factors
  • Risk Assessment
  • Risk Factors
  • Risk Reduction Behavior*
  • Smoking / adverse effects
  • Smoking / epidemiology
  • Smoking Cessation

Substances

  • Biomarkers
  • Blood Glucose
  • Cholesterol