Impact of spontaneous intracerebral hemorrhage on cognitive functioning: An update

Rev Neurol (Paris). 2017 Jul-Aug;173(7-8):481-489. doi: 10.1016/j.neurol.2017.06.010. Epub 2017 Aug 31.

Abstract

Intracerebral hemorrhage (ICH) accounts for 15% of all strokes and approximately 50% of stroke-related mortality and disability worldwide. Patients who have experienced ICH are at high risk of negative outcome, including stroke and cognitive disorders. Vascular cognitive impairment are frequently seen after brain hemorrhage, yet little is known about them, as most studies have focused on neuropsychological outcome in ischemic stroke survivors, using well-documented acute and chronic cognitive scores. However, recent evidence supports the notion that ICH and dementia are closely related and each increases the risk of the other. The location of the lesion also plays a significant role as regards the neuropsychological profile, while the pathophysiology of ICH can indicate a specific pattern of dysfunction. Several cognitive domains may be affected, such as language, memory, executive function, processing speed and gnosis.

Keywords: Cerebral amyloid angiopathy; Hypertension; Intracerebral hemorrhage; Strategic hemorrhage; Vascular cognitive impairment.

Publication types

  • Review

MeSH terms

  • Cerebral Hemorrhage / complications*
  • Cerebral Hemorrhage / physiopathology
  • Cerebral Hemorrhage / psychology*
  • Cerebral Hemorrhage / therapy
  • Cognition / physiology*
  • Cognition Disorders / etiology
  • Cognition Disorders / psychology
  • Cognition Disorders / therapy
  • Executive Function / physiology
  • Humans