1 aDepartment of Pharmacology, CHU Caen bNormandie Univ, UNICAEN, CHU Caen, EA 4650, Signalisation, électrophysiologie et imagerie des lésions d'ischémie-reperfusion myocardique, Caen, France cDepartment of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan dDepartment of Biochemistry ePôle Réanimations Anesthésie SAMU/SMUR fDepartment of Cardiology gDepartment of Biostatistics and Clinical Research, CHU de Caen hNormandie Univ, UNICAEN, CHU Caen, EA 2656, Groupe de Recherche sur l'Adaptation Microbienne (GRAM 2.0), Caen, France.