Abstract
The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction. In 28 days after ischemia/reperfusion injury, Semax diminished the growth of sympathetic innervation of ventricular septum, although it produced no effect on the density of β1 and β2 adrenoceptors.
Keywords:
Semax; autonomic nervous system; myocardial infarction.
MeSH terms
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Adrenocorticotropic Hormone / analogs & derivatives
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Adrenocorticotropic Hormone / therapeutic use
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Animals
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Male
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Myocardial Infarction / drug therapy
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Myocardial Infarction / metabolism*
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Peptide Fragments / therapeutic use
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Prostate / drug effects
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Prostate / metabolism
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Prostate / pathology
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Prostatitis / drug therapy
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Prostatitis / metabolism*
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Quercetin / analogs & derivatives
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Quercetin / therapeutic use
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Rats
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Rats, Wistar
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Sympathetic Nervous System / drug effects
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Sympathetic Nervous System / metabolism
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Sympathetic Nervous System / pathology
Substances
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Peptide Fragments
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ACTH (4-7), Pro-Gly-Pro-
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Adrenocorticotropic Hormone
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Quercetin
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taxifolin