Evaluation of Prognostic Factors and Determinants in Surgical Sperm Retrieval Procedures in Azoospermic Patients

Med Arch. 2017 Aug;71(4):243-245. doi: 10.5455/medarh.2017.71.243-245.

Abstract

Introduction: Main categorisation of azospermic is in two grups: nonobstructive azoospermia (NOA) and obstructive azoospermia (OA). We had evaluation of prognostic factors and determinants in sperm retrieval procedures in azoospermic patients.

Methods: Retrospective evaluation observed 21 selected patients with NOA and OA azoospermia, after that complete history, physical examination with ultarsound volume of testis and hormonal profile. Hormonal profile included: follicle stimulating hormone (FSH), luteinizing hormone (LH), testosteron (T) and prolactin (P) serum levels. Also karyotype and Y-deletion analysis were done and analyzed.

Results: 9 OA patients (42,9%) were undergone for TESE operation and 12 NOA patients (57,1%) for Micro-TESE operation. All TESE procedures were positive (100%). Micro-TESE in 12 selected NOA patients, 5 patients (41,6%) were positive and 7 patients (58,4%) negative. Patients testicular size, serum FSH and testosterone level showed correlation in success of sperm retrieval procedures.

Conclusion: TESE is elected procedure for obstructive azospermia (OA). Micro-TESE is appropriate sperm retrieval procedurec for patients with non-obstructive azoospermia (NOA) and correlate with high FSH and small volume of testis.

Keywords: Azoospermia; Micro/TESE; prognostic factors.

MeSH terms

  • Adult
  • Azoospermia / blood
  • Azoospermia / pathology
  • Azoospermia / surgery*
  • Follicle Stimulating Hormone / blood
  • Humans
  • Luteinizing Hormone / blood
  • Male
  • Organ Size
  • Prognosis
  • Prolactin / blood
  • Retrospective Studies
  • Sperm Retrieval* / instrumentation
  • Testis / pathology
  • Testis / surgery
  • Testosterone / blood
  • Treatment Outcome

Substances

  • Testosterone
  • Prolactin
  • Luteinizing Hormone
  • Follicle Stimulating Hormone