Abstract
Intravenous immunoglobulin (IVIG) is a widely used agent as the first choice of treatment of immune thrombocytopenic purpura (ITP). IVIG has several side effects, but it is a relatively safe treatment. Life-threatening thrombosis has been reported in adults and rarely in children. We report a case of a 14-year-old boy with dural venous sinus thrombosis and pulmonary embolism after treatment with IVIG for ITP. The patient was treated with low-molecular-weight heparin followed by warfarin and the symptoms were recovered. If a patient with ITP shows mental change or respiratory difficulty, we should consider thrombosis as well as hemorrhage.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Anticoagulants / therapeutic use
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Biopsy
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Bone Marrow / pathology
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Hematologic Tests
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Heparin, Low-Molecular-Weight / therapeutic use
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Humans
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Immunoglobulins, Intravenous / administration & dosage
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Magnetic Resonance Angiography
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Male
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Pulmonary Embolism / diagnosis*
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Pulmonary Embolism / drug therapy
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Pulmonary Embolism / etiology*
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Purpura, Thrombocytopenic, Idiopathic / complications*
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Purpura, Thrombocytopenic, Idiopathic / diagnosis
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Purpura, Thrombocytopenic, Idiopathic / therapy
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Sinus Thrombosis, Intracranial / diagnosis*
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Sinus Thrombosis, Intracranial / drug therapy
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Sinus Thrombosis, Intracranial / etiology*
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Tomography, X-Ray Computed
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Treatment Outcome
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Venous Thrombosis / diagnosis
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Venous Thrombosis / etiology
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Warfarin / therapeutic use
Substances
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Anticoagulants
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Heparin, Low-Molecular-Weight
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Immunoglobulins, Intravenous
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Warfarin