Population Pharmacokinetics of Intravenous Busulfan in Japanese Pediatric Patients With Primary Immunodeficiency Diseases

J Clin Pharmacol. 2018 Mar;58(3):327-331. doi: 10.1002/jcph.1027. Epub 2017 Oct 27.

¹ Department of Pharmacy, Medical Hospital, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
² Division of Pharmaceutical Care Sciences, Center for Social Pharmacy and Pharmaceutical Care Sciences, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan.
³ Community Pediatrics, Perinatal and Maternal Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
⁴ Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
⁵ Department of Pharmacokinetics and Pharmacodynamics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

No abstract available

Keywords: busulfan; children; hematopoietic stem cell transplantation; immunodeficiency; population pharmacokinetics.

MeSH terms