Respiratory Viral Infections in Solid Organ and Hematopoietic Stem Cell Transplantation

Clin Chest Med. 2017 Dec;38(4):707-726. doi: 10.1016/j.ccm.2017.07.012. Epub 2017 Sep 20.

Abstract

Respiratory viruses are common in solid organ and hematopoietic stem cell transplant recipients and a recognized cause of significant morbidity and mortality. Epidemiology, risk factors, and attributable mortality in both populations are reviewed. In addition, virus-specific prevention and treatment options, including emerging investigational therapies, are discussed for respiratory syncytial virus, influenza, adenovirus, parainfluenza, and other respiratory viruses.

Keywords: Hematopoietic stem cell transplant; Respiratory virus; Solid organ transplant.

Publication types

  • Review

MeSH terms

  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Hematopoietic Stem Cell Transplantation / methods
  • Humans
  • Respiratory Tract Infections / etiology*
  • Respiratory Tract Infections / pathology
  • Respiratory Tract Infections / virology
  • Transplantation Conditioning / adverse effects*
  • Transplantation Conditioning / methods