Factors Associated With 30-Day Mortality Rate in Respiratory Infections Caused by Streptococcus pneumoniae

Clin Infect Dis. 2018 Apr 3;66(8):1282-1285. doi: 10.1093/cid/cix999.

Abstract

In multivariable analysis of associations between initial antibiotic therapy and clinical outcomes in 5005 patients with microbiologically confirmed Streptococcus pneumoniae infections, "discordant" empiric antibiotic therapy was not associated with 30-day mortality rate (hazard ratio, 0.94; 95% confidence interval, .67-1.32).

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Bacteremia / mortality
  • Female
  • Humans
  • Male
  • Multivariate Analysis
  • Penicillins / therapeutic use*
  • Pneumococcal Infections / drug therapy
  • Pneumococcal Infections / microbiology
  • Pneumococcal Infections / mortality*
  • Proportional Hazards Models
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / microbiology
  • Respiratory Tract Infections / mortality*
  • Retrospective Studies
  • Streptococcus pneumoniae / drug effects*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Penicillins