Plaque-like Myofibroblastic Tumor: 2 Cases of This Unusual Dermal Tumor Which Occurs in Infancy and Early Childhood

Pediatr Dev Pathol. 2018 Sep-Oct;21(5):444-448. doi: 10.1177/1093526617746807. Epub 2017 Dec 9.

Abstract

Plaque-like myofibroblastic tumor (PLMT) is a rare dermal spindle cell tumor which occurs in infancy or childhood within the first 4 years of life. The tumor is often pruritic and mostly presents on the lower back. We describe 2 cases with characteristic clinical and histological features of this entity, thus adding to the 10 cases which have so far been reported. Histologically, the lesion resembles a dermatofibroma. However, diffuse and uniform immunohistochemical staining with smooth muscle actin favors a myofibroblastic lineage. PLMT should be considered in the differential diagnosis of a dermal spindle cell tumor in the pediatric age-group.

Keywords: dermatofibroma; infancy; plaque-like myofibroblastic tumor; smooth muscle actin.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Infant
  • Male
  • Neoplasms, Muscle Tissue / pathology*
  • Skin / pathology*
  • Skin Neoplasms / pathology*