1 Medical Intensive Care Unit, University Hospital Center, Nantes, France; Clinical Research Unit, University Hospital Center, Nantes, France; Medical-Surgical Intensive Care Unit, District Hospital Center, La Roche-sur-Yon, France; Medical Intensive Care Unit - Hopital de la Croix Rousse, Hospices Civils de Lyon, Lyon, France; Bacteriological Laboratory, District Hospital Center, La Roche-sur-Yon, France; Medical Intensive Care Unit, University Hospital Center, Nantes, France.