Non-surgical intervention for retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: treatment with ulipristal acetate

BMJ Case Rep. 2018 Jan 3:2018:bcr2017222693. doi: 10.1136/bcr-2017-222693.

Abstract

This case report describes a very rare coexistence of retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: benign metastasising leiomyoma (BML). Despite surgical treatment growth of multiple nodules in the lungs, omentum, mesenterium and retroperitoneum was observed by CT scan. We started off-label ulipristal acetate treatment with impressive results. The lesions on the CT scan disappeared, and the patient was asymptomatic after treatment.

Keywords: cancer - see oncology; obstetrics, gynaecology and fertility.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Contraceptive Agents, Female / therapeutic use
  • Diagnosis, Differential
  • Female
  • Humans
  • Leiomyoma / drug therapy*
  • Leiomyoma / pathology
  • Leiomyoma / surgery
  • Lung / pathology
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary*
  • Norpregnadienes / administration & dosage
  • Norpregnadienes / therapeutic use*
  • Omentum / diagnostic imaging
  • Omentum / pathology
  • Retroperitoneal Neoplasms / diagnostic imaging
  • Retroperitoneal Neoplasms / pathology
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Contraceptive Agents, Female
  • Norpregnadienes
  • ulipristal acetate