Pathological overview of chronic gastritis in Senegal: results of upper gastrointestinal tract endoscopies

Med Sante Trop. 2017 Nov 1;27(4):439-442. doi: 10.1684/mst.2017.0740.

Abstract

The aim of this study was to determine the prevalence of gastritis in upper endoscopies performed for clinical signs suggestive of gastritis among 100 patients in a tropical country. Chronic gastritis (CG) was present among 81%, including CG due to Helicobacter pylori (n = 61, 75.3%), reactive CG (n = 14), and autoimmune CG (n = 6). The gastritis was located in the stomach antrum (55.7%, n = 40), fundus (3.3%, n = 2), or both (41% n = 25). Median age at diagnosis was 35 years (14/80). This CG was associated with signs of stomach activity (27.9%, n = 17), atrophy (13.1%, n = 8), metaplasia (9.8%, n = 6), and dysplasia (8.2%, n = 5). The 14 patients with reactive CG had a mean age of 31 years and all were coffee-drinkers. This CG was not associated with precancerous lesions. Autoimmune CG, present in 6% of the population, was diagnosed at a mean age of 55 years (range: 45; 67). These involved fundal atrophy with metaplasia and were associated with dysplastic lesions (66.7% n = 4).

Keywords: Helicobacter Pylori; Senegal; gastritis; gastroscopy; pathology.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Autoimmune Diseases / complications
  • Chronic Disease
  • Endoscopy, Gastrointestinal*
  • Female
  • Gastritis / etiology*
  • Gastritis / pathology*
  • Helicobacter Infections / complications
  • Helicobacter pylori
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Senegal / epidemiology
  • Young Adult