Transcriptome datasets of macrophages infected with different strains of Leptospira spp

Erivelto Corrêa de Araújo Junior; Leandro Encarnação Garcia; Larissa Martins Melo; Jaqueline Poleto Bragato; Valéria Marçal Félix de Lima; Juliana Regina Peiró; Flavia Lombardi Lopes; Márcia Marinho

doi:10.1016/j.dib.2017.12.042

Transcriptome datasets of macrophages infected with different strains of Leptospira spp

Data Brief. 2017 Dec 21:16:1044-1050. doi: 10.1016/j.dib.2017.12.042. eCollection 2018 Feb.

Authors

Erivelto Corrêa de Araújo Junior¹, Leandro Encarnação Garcia¹, Larissa Martins Melo², Jaqueline Poleto Bragato², Valéria Marçal Félix de Lima², Juliana Regina Peiró², Flavia Lombardi Lopes¹, Márcia Marinho¹

Affiliations

¹ Department of Support, Production and Animal Health, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, SP, Brazil.
² Department of Clinic, Surgery and Animal Reproduction, São Paulo State University (Unesp), School of Veterinary Medicine, Araçatuba, SP, Brazil.

Abstract

The datasets reported herein provide information about microarray experiment of macrophage cell line J774A.1 infected with three different strains of Leptospira spp. Transcriptomic profiles were generated using Affymetrix® Mouse Gene 2.1 ST Array Strip. Data was normalized and statically process, p-value < 0.01, FDR < 0.05 and log2 fold change (± 2). The microarray raw data are available in Gene Expression Omnibus (GEO) under accession number GSE105141.

Keywords: Leptospira; Macrophage; Microarray.