Plasma cell-free DNA methylation: a liquid biomarker of hepatic fibrosis

Gut. 2018 Oct;67(10):1907-1908. doi: 10.1136/gutjnl-2017-315668. Epub 2018 Jan 20.

Authors

Affiliations

¹ Department of Gastroenterology and Hepatology, School of Medicine, Koç University, Istanbul, Turkey.
² Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
³ Department of Internal Medicine, University of Erlangen-Nuremberg, Erlangen, Germany.
⁴ Liver Transplantation Unit, Istanbul Bilim University, Florence Nightingale Hospital, Istanbul, Turkey.

^# Contributed equally.

No abstract available

Keywords: hepatic fibrosis; hepatitis B; hepatocellular carcinoma; liver.

Publication types

Letter
Validation Study

MeSH terms

Biomarkers / analysis
Biomarkers / metabolism
Carcinoma, Hepatocellular* / blood
Carcinoma, Hepatocellular* / complications
Carcinoma, Hepatocellular* / ethnology
Cell-Free Nucleic Acids* / analysis
Cell-Free Nucleic Acids* / metabolism
DNA Methylation
Disease Progression
Female
Hepatitis B, Chronic* / blood
Hepatitis B, Chronic* / complications
Hepatitis B, Chronic* / ethnology
Humans
Liver Cirrhosis* / blood
Liver Cirrhosis* / diagnosis
Liver Cirrhosis* / etiology
Liver Neoplasms / blood
Liver Neoplasms / complications
Liver Neoplasms / ethnology
Liver* / metabolism
Liver* / pathology
Male
Middle Aged
Non-alcoholic Fatty Liver Disease* / blood
Non-alcoholic Fatty Liver Disease* / complications
Non-alcoholic Fatty Liver Disease* / ethnology
PPAR gamma* / analysis
PPAR gamma* / metabolism
Promoter Regions, Genetic
Turkey / epidemiology

Substances

Biomarkers
Cell-Free Nucleic Acids
PPAR gamma

Grants and funding