Short-term ibrutinib therapy suppresses skin test responses and eliminates IgE-mediated basophil activation in adults with peanut or tree nut allergy

J Allergy Clin Immunol. 2018 May;141(5):1914-1916.e7. doi: 10.1016/j.jaci.2017.12.987. Epub 2018 Jan 31.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenine / analogs & derivatives
  • Adult
  • Arachis / immunology*
  • Basophils / drug effects*
  • Basophils / immunology
  • Female
  • Humans
  • Immunoglobulin E / immunology*
  • Male
  • Nut Hypersensitivity / drug therapy*
  • Nut Hypersensitivity / immunology
  • Peanut Hypersensitivity / drug therapy*
  • Peanut Hypersensitivity / immunology
  • Piperidines
  • Pyrazoles / therapeutic use*
  • Pyrimidines / therapeutic use*
  • Skin Tests / methods

Substances

  • Piperidines
  • Pyrazoles
  • Pyrimidines
  • ibrutinib
  • Immunoglobulin E
  • Adenine

Associated data

  • ClinicalTrials.gov/NCT03149315