[Long-Term Survival after Resection for Repeated Abdominal Wall Recurrence of Gallbladder Cancer]

Gan To Kagaku Ryoho. 2017 Nov;44(12):1317-1319.
[Article in Japanese]

Abstract

We report the case of a 79-year-old woman with repeated abdominal wall recurrence of gallbladder cancer. The original diagnosis was gallbladder carcinoma. She underwent open liver bed dissection and lymph node dissection. Postoperative pathological examination indicated T2N1M0, Stage III disease. She received 6 courses of postoperative chemotherapy with gemcitabine. Two years and 2 months after the surgery, we detected a 13 mm mass under the abdominal wall scar on CT, and we resected this tumor. Pathological findings indicated adenocarcinoma, which was found to be metastasis of the gallbladder cancer. She was treated with S-1 for 8 courses postoperatively. However, 3 years 4 months after the first surgery, a tumor of 22mm was detected in the abdominal wall on the caudal side away from the previous tumor excision site. We resected the abdominal wall including the tumor. The pathological examination revealed adenocarcinoma, which was again metastasis from gallbladder cancer. The increase of CA19-9 was confirmed around 4 years and 7months after the first operation. An abdominal wall tumor of 45mm was detected in contact with the iliac bone near the last excision site and it proved to be a recurrence of gallbladder carcinoma. We performed abdominal wall tumor resection, again identifying adenocarcinoma, which was the third recurrence of gallbladder cancer. Despite continued abdominal wall recurrence, she is alive and well without metastasis for more than 5 years.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / pathology
  • Abdominal Neoplasms / secondary
  • Abdominal Neoplasms / surgery*
  • Abdominal Wall / pathology
  • Abdominal Wall / surgery*
  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / secondary
  • Adenocarcinoma / surgery*
  • Aged
  • Antimetabolites, Antineoplastic / therapeutic use
  • Deoxycytidine / analogs & derivatives
  • Deoxycytidine / therapeutic use
  • Female
  • Gallbladder Neoplasms / drug therapy
  • Gallbladder Neoplasms / pathology*
  • Gallbladder Neoplasms / surgery
  • Gemcitabine
  • Humans
  • Recurrence
  • Time Factors

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Gemcitabine