Perioperative management of a redo aortic root replacement in a patient with severe factor XI deficiency

J Card Surg. 2018 Feb;33(2):86-89. doi: 10.1111/jocs.13526. Epub 2018 Feb 4.

Abstract

Factor XI deficiency is associated with significant bleeding in the setting of trauma and surgery. We present a patient with FXI deficiency and multiple red blood cell allo-antibodies requiring repeat aortic root replacement and discuss the perioperative management of patients with FXI deficiency undergoing cardiac surgery.

Keywords: aorta and great vessels; valve repair/replacement.

Publication types

  • Case Reports

MeSH terms

  • Aminocaproic Acid / administration & dosage
  • Aorta / surgery*
  • Aortic Aneurysm / complications
  • Aortic Aneurysm / surgery*
  • Aortic Valve / surgery
  • Blood Vessel Prosthesis Implantation*
  • Erythrocyte Transfusion
  • Factor VIIa / administration & dosage
  • Factor XI Deficiency / complications*
  • Heart Valve Prosthesis Implantation
  • Hepatitis C / complications
  • Humans
  • Male
  • Middle Aged
  • Perioperative Care / methods*
  • Plasma
  • Recombinant Proteins / administration & dosage
  • Reoperation*
  • Severity of Illness Index
  • Sternotomy
  • Treatment Outcome

Substances

  • Recombinant Proteins
  • Factor VIIa
  • Aminocaproic Acid