State-of-the-Art Modalities for Peripheral Lung Nodule Biopsy

Clin Chest Med. 2018 Mar;39(1):125-138. doi: 10.1016/j.ccm.2017.11.007. Epub 2017 Dec 14.

Abstract

Lung nodules are being increasingly detected, particularly with lung cancer screening with low-dose computed tomography. Although the vast majority of lung nodules are benign, many often require tissue diagnosis. Several modalities to obtain diagnostic tissue from peripheral lung nodules are available. Bronchoscopic modalities such as radial ultrasound and electromagnetic navigational bronchoscopy are becoming increasingly used because of their superior safety profile and improving diagnostic yield. Although these modalities continue to become more advanced, newer and complementary technologies appear promising.

Keywords: ENB; Electromagnetic navigational bronchoscopy; Lung cancer; Peripheral pulmonary nodules; Radial ultrasound; Solitary pulmonary nodule.

Publication types

  • Review

MeSH terms

  • Early Detection of Cancer / methods*
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology
  • Solitary Pulmonary Nodule / diagnosis*
  • Solitary Pulmonary Nodule / pathology