Bilateral acute angle-closure glaucoma following tramadol subcutaneous administration

BMC Ophthalmol. 2018 Feb 17;18(1):50. doi: 10.1186/s12886-018-0715-4.

Abstract

Background: To report a case of bilateral acute angle closure-glaucoma following the use of subcutaneous Tramadol.

Case presentation: A 42-year-old healthy man with unremarkable past medical and ocular history, was admitted to the Orthopedic Department for surgical treatment of a bilateral open fracture of the femur following a road accident. Three hoursafterTramadolsubcutaneous injection, the patient complained of a bilateral acute painful visual loss with persistent vomiting. An ocular examination showed bilateral acute angle-closure-glaucoma. The patient was treated with topical anti-glaucoma therapy and intravenous Mannitol 20%.After resolution of ocular hypertension attack, NdYag laser peripheral iridotomy was performed on both eyes. After a follow-up period of 7 days visual acuity improved to 20/20 in both eyes and intraocular pressure returned to normal levels.

Conclusions: This case highlights the risk of developing bilateral acute angle-closure glaucoma after Tramadol administration.

Keywords: Angle closure glaucomaMydriasisTramadolAnterior segment OCT..

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / adverse effects*
  • Glaucoma, Angle-Closure / chemically induced*
  • Humans
  • Injections, Subcutaneous
  • Intraocular Pressure
  • Male
  • Tramadol / administration & dosage
  • Tramadol / adverse effects*

Substances

  • Analgesics, Opioid
  • Tramadol