Metastatic cardiac tumors: from clinical presentation through diagnosis to treatment

BMC Cancer. 2018 Feb 20;18(1):202. doi: 10.1186/s12885-018-4070-x.

Abstract

Background: To evaluate the prevalence of metastatic tumors involving the myocardium and study their presentation in order to increase awareness to their existence.

Methods: Pathological reports from Sheba Medical Center (Israel, January 1, 2010 through December 31, 2015) and medical records from The Institute for Cardiovascular Diseases of Vojvodina, Sremska Kamenica (Serbia, 23 years period) were screened for cases of metastatic cardiac tumors. Medical, radiological and pathological data of identified cases was retrieved and reviewed.

Results: Out of thousands of registered cardiac surgeries we found less than a dozen cases of metastatic cardiac tumors classified as melanoma, carcinomas of lung, colon and kidney and sarcomas of uterine origin. We found that metastatic cardiac tumors comprised 15.8% of all the cardiac tumors.

Conclusions: Metastatic cardiac tumors are extremely rare. As new diagnostic technologies and improved survival of oncological patients may increase the incidence of metastatic cardiac tumors in the future, awareness to their existence and knowledge of their presentation are key factors in their timely recognition.

Keywords: Melanoma; Metastatic carcinoma; Metastatic cardiac tumors; Metastatic sarcoma; Myocardium.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • Combined Modality Therapy
  • Fatal Outcome
  • Female
  • Heart Neoplasms / diagnosis*
  • Heart Neoplasms / epidemiology
  • Heart Neoplasms / secondary*
  • Heart Neoplasms / therapy*
  • Humans
  • Male
  • Melanoma / pathology
  • Middle Aged
  • Multimodal Imaging
  • Myocardium / pathology
  • Neoplasms, Germ Cell and Embryonal
  • Population Surveillance
  • Prevalence
  • Treatment Outcome