Surgical Treatment of Metastatic Colorectal Cancer

Surg Oncol Clin N Am. 2018 Apr;27(2):377-399. doi: 10.1016/j.soc.2017.11.010. Epub 2017 Dec 15.

Abstract

Surgical treatment of metastatic colorectal cancer offers a chance for cure or prolonged survival, particularly for those with more favorable prognostic factors and limited tumor burden. The treatment plan requires multidisciplinary evaluation because multiple therapy options exist. Advanced surgical techniques, adjuncts to resection, and modern chemotherapy all contribute to best outcomes for patients with hepatic metastases. Although cure is less common for patients with metastasis to lung or peritoneum, surgical resection for the former and cytoreduction and intraperitoneal chemotherapy for the latter may help to achieve cancer control in selected patients.

Keywords: Colorectal cancer; Metastases; Stage IV; Surgery; Surgical management.

Publication types

  • Review

MeSH terms

  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / surgery*
  • Hepatectomy / methods*
  • Humans
  • Liver Neoplasms / secondary
  • Liver Neoplasms / surgery*
  • Prognosis