Hot topics in necrotising skin and soft tissue infections

Kordo Saeed; Silvano Esposito; Ian Gould; Tiziana Ascione; Matteo Bassetti; Eric Bonnet; Emilio Bouza; Monica Chan; Joshua S Davis; Giuseppe De Simone; Matthew Dryden; Thomas Gottlieb; Karolin Hijazi; David C Lye; Pasquale Pagliano; Christina Petridou; Elda Righi; John Segreti; Serhet Unal; Ata Nevzat Yalcin; International Society of Antimicrobial Chemotherapy

doi:10.1016/j.ijantimicag.2018.02.012

Hot topics in necrotising skin and soft tissue infections

Int J Antimicrob Agents. 2018 Jul;52(1):1-10. doi: 10.1016/j.ijantimicag.2018.02.012. Epub 2018 Mar 6.

Authors

Kordo Saeed¹, Silvano Esposito², Ian Gould³, Tiziana Ascione⁴, Matteo Bassetti⁵, Eric Bonnet⁶, Emilio Bouza⁷, Monica Chan⁸, Joshua S Davis⁹, Giuseppe De Simone², Matthew Dryden¹⁰, Thomas Gottlieb¹¹, Karolin Hijazi¹², David C Lye¹³, Pasquale Pagliano⁴, Christina Petridou¹⁴, Elda Righi⁵, John Segreti¹⁵, Serhet Unal¹⁶, Ata Nevzat Yalcin¹⁷; International Society of Antimicrobial Chemotherapy

Affiliations

¹ Department of Microbiology, Hampshire Hospitals NHS Foundation Trust, Basingstoke and Winchester, UK; University of Southampton, School of Medicine, Southampton, UK.
² Department of Infectious Diseases, University of Salerno, Salerno, Italy.
³ Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK.
⁴ AORN dei Colli Dept of Infectious Diseases, Naples, Italy.
⁵ Infectious Diseases Clinic, Department of Medicine University of Udine and Azienda Sanitaria Universitaria Integrata, Udine, Italy.
⁶ Department of Infectious Diseases, Hôpital Joseph Ducuing, Toulouse, France.
⁷ Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
⁸ Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.
⁹ Department of Infectious Diseases, John Hunter Hospital, Newcastle, NSW, Australia; and Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia.
¹⁰ Department of Microbiology, Hampshire Hospitals NHS Foundation Trust, Basingstoke and Winchester, UK; University of Southampton, School of Medicine, Southampton, UK; Public Health England, Porton Down, UK.
¹¹ Department of Microbiology & Infectious Diseases, Concord Hospital, Concord, NSW, Australia.
¹² Institute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen.
¹³ Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
¹⁴ Public Health England, Porton Down, UK.
¹⁵ Department of Infectious Diseases, Rush University Medical Center, Chicago, IL, USA.
¹⁶ Department of Infectious Diseases, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
¹⁷ Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

PMID: 29501822
DOI: 10.1016/j.ijantimicag.2018.02.012

No abstract available

Keywords: Gas gangrene; Intravenous immunoglobulin G; Necrotising fasciitis; Panton-Valentine leukocidin; Pyomyositis; Skin and soft tissue infections.

Publication types

Editorial
Review

MeSH terms

Administration, Intravenous
Bacterial Toxins / metabolism
Dermatomycoses / drug therapy
Dermatomycoses / etiology
Exotoxins / metabolism
Fasciitis, Necrotizing / diagnosis
Fasciitis, Necrotizing / drug therapy
Fasciitis, Necrotizing / etiology*
Gas Gangrene / drug therapy
Gas Gangrene / etiology
Humans
Immunocompromised Host
Immunoglobulins / administration & dosage
Leukocidins / metabolism
Pyomyositis / drug therapy
Pyomyositis / etiology
Skin Diseases, Bacterial / drug therapy*
Skin Diseases, Bacterial / etiology*
Soft Tissue Infections / diagnosis
Soft Tissue Infections / drug therapy*
Soft Tissue Infections / etiology*
Staphylococcus aureus / metabolism
Staphylococcus aureus / pathogenicity
Substance Abuse, Intravenous

Substances

Bacterial Toxins
Exotoxins
Immunoglobulins
Leukocidins
Panton-Valentine leukocidin