Combating low birth weight due to malaria infection in pregnancy

James G Beeson; Michelle J L Scoullar; Philippe Boeuf

doi:10.1126/scitranslmed.aat1506

Combating low birth weight due to malaria infection in pregnancy

Sci Transl Med. 2018 Mar 7;10(431):eaat1506. doi: 10.1126/scitranslmed.aat1506.

Authors

James G Beeson^{1

2

3}, Michelle J L Scoullar^{4

3}, Philippe Boeuf^{4

3}

Affiliations

¹ Burnet Institute, Melbourne, Victoria, Australia. beeson@burnet.edu.au.
² Central Clinical School and Department of Microbiology, Monash University, Melbourne, Victoria, Australia.
³ Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
⁴ Burnet Institute, Melbourne, Victoria, Australia.

PMID: 29514997
DOI: 10.1126/scitranslmed.aat1506

Abstract

Decreased l-arginine and nitric oxide bioavailability in pregnant women with malaria contributes to low birth weight, suggesting that l-arginine supplementation could be a potential treatment (McDonald et al).

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Arginine / therapeutic use
Birth Weight / drug effects
Female
Humans
Infant, Low Birth Weight
Infant, Newborn
Malaria / drug therapy*
Malaria / metabolism
Malaria / prevention & control*
Nitric Oxide / metabolism
Pregnancy

Substances

Nitric Oxide
Arginine