From 3D Organoids back to 2D Enteroids

Jonathan Braverman; Ömer H Yilmaz

doi:10.1016/j.devcel.2018.02.016

From 3D Organoids back to 2D Enteroids

Dev Cell. 2018 Mar 12;44(5):533-534. doi: 10.1016/j.devcel.2018.02.016.

Authors

Jonathan Braverman¹, Ömer H Yilmaz²

Affiliations

¹ Koch Institute for Integrative Cancer Research at MIT and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
² Koch Institute for Integrative Cancer Research at MIT and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address: ohyilmaz@mit.edu.

PMID: 29533766
DOI: 10.1016/j.devcel.2018.02.016

Abstract

In this issue of Developmental Cell, Thorne et al. (2018) describe a simple, scalable method to culture 2D enteroid monolayers that surprisingly recapitulates many of the features of 3D organoid cultures and in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments.

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MeSH terms

Intestines*
Organoids*