1 Colorado Pulmonary Outcomes Research Group, Department of Medicine, University of Colorado School of Medicine, Aurora, CO and Division of Pulmonary Sciences & Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO; Department of Medicine, University of Colorado School of Medicine, Aurora, CO; Colorado Pulmonary Outcomes Research Group, Department of Medicine, University of Colorado School of Medicine, Aurora, CO and Peak Statistical Services, Evergreen, CO; Department of Neurology, University of Colorado School of Medicine, Aurora, CO; Colorado Pulmonary Outcomes Research Group, Department of Medicine, University of Colorado School of Medicine, Aurora, CO and Division of Pulmonary Sciences & Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO; Colorado Pulmonary Outcomes Research Group, Department of Medicine, University of Colorado School of Medicine, Aurora, CO and Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO; Colorado Pulmonary Outcomes Research Group, Department of Medicine, University of Colorado School of Medicine, Aurora, CO and Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO; Colorado Pulmonary Outcomes Research Group, Department of Medicine, University of Colorado School of Medicine, Aurora, CO and Division of Pulmonary Sciences & Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO.