The CD20-specific engineered toxin antibody MT-3724 exhibits lethal effects against mantle cell lymphoma

Blood Cancer J. 2018 Mar 20;8(3):33. doi: 10.1038/s41408-018-0066-7.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, CD20 / metabolism*
  • Antineoplastic Agents, Immunological / pharmacology*
  • Antineoplastic Agents, Immunological / therapeutic use
  • Apoptosis / drug effects
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Cell Survival / drug effects
  • Humans
  • Immunotoxins / pharmacology*
  • Immunotoxins / therapeutic use
  • Lymphoma, Mantle-Cell / drug therapy
  • Lymphoma, Mantle-Cell / metabolism*
  • Shiga Toxin 1 / pharmacology
  • Single-Chain Antibodies / pharmacology

Substances

  • Antigens, CD20
  • Antineoplastic Agents, Immunological
  • Immunotoxins
  • Shiga Toxin 1
  • Single-Chain Antibodies