Vecuronium bromide is an FDA-approved peripherally acting, monoquarternary, steroidal, non-depolarizing neuromuscular blocker with an intermediate duration of action used during general anesthesia to facilitate endotracheal intubation to aid in surgical relaxation and, less commonly, in the intensive care setting to achieve paralysis to facilitate mechanical ventilation for adequately sedated patients. This neuromuscular blocking agent is often used to facilitate endotracheal intubation and surgical relaxation in patients under general anesthesia. This activity provides an overview of the FDA-approved indications, mechanism of action, methods, timing of administration, significant adverse effects, contraindications, toxicity, and monitoring for vecuronium use to be successfully dosed as part of a general anesthesia process. It also highlights adult dosage, dosage in specific patient populations, pharmacokinetics, warnings, and precautions for Vecuronium bromide. Additionally, this activity focuses on the role of interprofessional team members to achieve better patient safety and enhance therapeutic outcomes when vecuronium administration is desired.
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