Partial restoration of CD20 protein expression and rituximab sensitivity after treatment with azacitidine in CD20-negative transformed diffuse large B cell lymphoma after using rituximab

Ann Hematol. 2018 Nov;97(11):2253-2255. doi: 10.1007/s00277-018-3354-1. Epub 2018 May 3.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antigens, CD20 / biosynthesis*
  • Antigens, CD20 / genetics
  • Antigens, Neoplasm / biosynthesis*
  • Antigens, Neoplasm / genetics
  • Antimetabolites, Antineoplastic / pharmacology
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Azacitidine / pharmacology
  • Azacitidine / therapeutic use*
  • Bendamustine Hydrochloride / administration & dosage
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / adverse effects
  • Cytarabine / administration & dosage
  • Dexamethasone / administration & dosage
  • Doxorubicin / administration & dosage
  • Doxorubicin / adverse effects
  • Drug Resistance, Neoplasm
  • Etoposide / administration & dosage
  • Fatal Outcome
  • Gene Expression Regulation, Neoplastic / drug effects*
  • Humans
  • Lymphoma, Follicular / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / chemically induced
  • Lymphoma, Large B-Cell, Diffuse / drug therapy*
  • Lymphoma, Large B-Cell, Diffuse / genetics
  • Lymphoma, Large B-Cell, Diffuse / metabolism
  • Male
  • Middle Aged
  • Molecular Targeted Therapy*
  • Myelodysplastic Syndromes / chemically induced
  • Myelodysplastic Syndromes / drug therapy*
  • Neoplasms, Second Primary / chemically induced
  • Neoplasms, Second Primary / drug therapy*
  • Neoplasms, Second Primary / genetics
  • Neoplasms, Second Primary / metabolism
  • Prednisone / administration & dosage
  • Prednisone / adverse effects
  • Rituximab / administration & dosage
  • Rituximab / pharmacology
  • Rituximab / therapeutic use*
  • Vincristine / administration & dosage
  • Vincristine / adverse effects

Substances

  • Antigens, CD20
  • Antigens, Neoplasm
  • Antimetabolites, Antineoplastic
  • Cytarabine
  • Rituximab
  • Vincristine
  • Etoposide
  • Dexamethasone
  • Doxorubicin
  • Cyclophosphamide
  • Bendamustine Hydrochloride
  • Azacitidine
  • Prednisone

Supplementary concepts

  • CHASE protocol
  • CHOP protocol