Sleep: Short Sleepers Should Keep Count of Their Hypocretin Neurons

Louis C Leung; Philippe Mourrain

doi:10.1016/j.cub.2018.03.006

Sleep: Short Sleepers Should Keep Count of Their Hypocretin Neurons

Curr Biol. 2018 May 7;28(9):R558-R560. doi: 10.1016/j.cub.2018.03.006.

Authors

Louis C Leung¹, Philippe Mourrain²

Affiliations

¹ Department of Psychiatry and Behavioral Sciences, Stanford Center for Sleep Sciences and Medicine, Stanford, CA 94305, USA.
² Department of Psychiatry and Behavioral Sciences, Stanford Center for Sleep Sciences and Medicine, Stanford, CA 94305, USA; INSERM 1024, Ecole Normale Supérieure Paris, 75005, France. Electronic address: mourrain@stanford.edu.

PMID: 29738730
DOI: 10.1016/j.cub.2018.03.006

Abstract

Sleep durations vary greatly across animals from 2 to 20 hours with no clear explanation. A small Mexican cavefish reveals how the brain can adapt to increase its wake-stabilizing hypocretin circuit and dramatically reduce sleep, likely to allow adaptive foraging.

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MeSH terms

Animals
Intracellular Signaling Peptides and Proteins*
Neurons
Neuropeptides*
Orexins
Prosencephalon
Sleep

Substances

Intracellular Signaling Peptides and Proteins
Neuropeptides
Orexins