Oxygen Therapy in the Delivery Room: What Is the Right Dose?

Clin Perinatol. 2018 Jun;45(2):293-306. doi: 10.1016/j.clp.2018.01.014. Epub 2018 Mar 7.

Abstract

Oxygen is the most commonly used medicine used during neonatal resuscitation in the delivery room. Oxygen therapy in delivery room should be used judiciously to avoid oxygen toxicity while delivering sufficient oxygen to prevent hypoxia. Measurement of appropriate oxygenation relies on pulse oximetry, but adequate ventilation and perfusion are equally important for oxygen delivery. In this article, we review oxygenation while transitioning from fetal to neonatal life, the importance of appropriate oxygen therapy, its measurement in the delivery room, and current recommendations for oxygen therapy and its limitations.

Keywords: Delivery room; Newborn; Oxygen; Oxygen saturation; Resuscitation.

Publication types

  • Review

MeSH terms

  • Asphyxia Neonatorum / diagnosis
  • Asphyxia Neonatorum / therapy*
  • Delivery Rooms*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Labor, Obstetric
  • Male
  • Oximetry / methods
  • Oxygen / therapeutic use
  • Oxygen Consumption / physiology
  • Oxygen Inhalation Therapy / methods*
  • Practice Guidelines as Topic*
  • Pregnancy
  • Prognosis
  • Resuscitation / methods*
  • Risk Assessment
  • Treatment Outcome

Substances

  • Oxygen