The Ensembl Genome Browser: Strategies for Accessing Eukaryotic Genome Data

Methods Mol Biol. 2018:1757:115-139. doi: 10.1007/978-1-4939-7737-6_6.

Abstract

The Ensembl Genome Browser provides a wealth of freely available genomic data that can be accessed for many purposes by genetics, genomics, and molecular biology researchers. Herein we present two protocols for exploring different aspects of these data: a phenotype and its associated variants and genes, and a promoter and the epigenetic marks and protein-binding activity associated with it. These workflows illustrate a subset of the data types available through the Ensembl Browser, and can be considered a springboard for further exploration.

Keywords: Ensembl; Epigenetic mark; Eukaryotic genomes; Phenotypes; Variants.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods
  • Databases, Genetic*
  • Epigenomics
  • Genetic Variation
  • Genome*
  • Genomics / methods*
  • Phenotype
  • Search Engine
  • Software*
  • User-Computer Interface
  • Web Browser*