Biological Approaches for Disease Control in Aquaculture: Advantages, Limitations and Challenges

Trends Microbiol. 2018 Nov;26(11):896-903. doi: 10.1016/j.tim.2018.05.002. Epub 2018 May 22.

Abstract

Although aquaculture activity has experienced a great development over the past three decades, infectious diseases have become a limiting factor for further intensification. Because the use of antibiotics has led to the widespread emergence of antibiotic resistance, the search for alternative environmentally friendly approaches is urgently needed. This Opinion paper offers an update on the successes and challenges of biological approaches for bacterial disease prevention and control in aquaculture. Although most of these approaches are still in research and development stages, some of them have shown promising results in field trials. Therefore, a better understanding of the mechanisms of action of these approaches will help to maximise their beneficial properties.

Keywords: antibiotic resistance; aquaculture; biological control approaches; diseases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Antibiotic Prophylaxis / adverse effects*
  • Antibiotic Prophylaxis / veterinary*
  • Aquaculture / methods*
  • Bacteria
  • Bacterial Infections / prevention & control*
  • Bacteriophages
  • Communicable Disease Control / methods
  • Drug Resistance, Microbial*
  • Fish Diseases / prevention & control
  • Phage Therapy / methods
  • Plant Extracts / therapeutic use
  • Prebiotics
  • Probiotics / therapeutic use
  • Quorum Sensing
  • Synbiotics
  • Vaccination / methods
  • Vaccines

Substances

  • Anti-Bacterial Agents
  • Plant Extracts
  • Prebiotics
  • Vaccines