Refocused linewidths less than 10 Hz in 1H solid-state NMR

Federico M Paruzzo; Gabriele Stevanato; Meghan E Halse; Judith Schlagnitweit; Daniele Mammoli; Anne Lesage; Lyndon Emsley

doi:10.1016/j.jmr.2018.06.001

Refocused linewidths less than 10 Hz in ¹H solid-state NMR

J Magn Reson. 2018 Aug:293:41-46. doi: 10.1016/j.jmr.2018.06.001. Epub 2018 Jun 2.

Authors

Federico M Paruzzo¹, Gabriele Stevanato¹, Meghan E Halse², Judith Schlagnitweit³, Daniele Mammoli⁴, Anne Lesage⁵, Lyndon Emsley⁶

Affiliations

¹ Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland.
² Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
³ Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden.
⁴ Department of Radiology, University of California, San Francisco 94158, USA.
⁵ Institut des Sciences Analytiques, Université de Lyon, 69100 Villeurbanne, France.
⁶ Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland. Electronic address: lyndon.emsley@epfl.ch.

PMID: 29890485
DOI: 10.1016/j.jmr.2018.06.001

Abstract

Coherence lifetimes in homonuclear dipolar decoupled ¹H solid-state NMR experiments are usually on the order of a few ms. We discover an oscillation that limits the lifetime of the coherences by recording spin-echo dephasing curves. We find that this oscillation can be removed by the application of a double spin-echo experiment, leading to coherence lifetimes of more than 45 ms in adamantane and more that 22 ms in β-AspAla, corresponding to refocused linewidths of less than 7 and 14 Hz respectively.

Keywords: Coherence lifetime; High-resolution; Homonuclear dipolar decoupling; Solid-state NMR; T(2)′ measurements.

Publication types

Research Support, Non-U.S. Gov't