Immediate Clinical Success After Percutaneous Ablation of Extra-adrenal Paraganglioma

Cardiovasc Intervent Radiol. 2018 Nov;41(11):1803-1806. doi: 10.1007/s00270-018-2015-z. Epub 2018 Jun 19.

Abstract

Paragangliomas (PGLs) are catecholamine-secreting neoplasms of chromaffin cells and represent a rare but curable cause of secondary hypertension. Surgery is the treatment of choice for symptomatic PGLs. A small (7 mm) extra-adrenal PGL was diagnosed in the right retroperitoneal space in a 19-year-old patient affected by symptomatic hypertension unresponsive to medical treatment. Indication to percutaneous radiofrequency ablation (RFA) was given by a multidisciplinary team on the basis of the size of the nodule, the surgical risks, the young age of the patient, and his wish to reduce as much as possible the post-interventional rehabilitation. To our knowledge, the use of percutaneous RFA in the treatment of retroperitoneal extra-adrenal primary paragangliomas has never been described. We describe its feasibility and the patient's clinical outcome.

Keywords: Hypertension; Paraganglioma; Percutaneous radiofrequency ablation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Catheter Ablation / methods*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Paraganglioma, Extra-Adrenal / diagnostic imaging
  • Paraganglioma, Extra-Adrenal / surgery*
  • Radiography, Interventional
  • Retroperitoneal Neoplasms / diagnostic imaging
  • Retroperitoneal Neoplasms / surgery*
  • Retroperitoneal Space / diagnostic imaging
  • Retroperitoneal Space / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult