Objective: To investigate theperiodic changes in onset of aortic dissection. Methods: The clinical data of 1 121 patients with acute aortic dissection from Hebei province, treated at Fuwai hospital from January 1, 2010 to December 31, 2016, were collected and analyzed retrospectively. The regularity for the onset of aortic dissection was analyzed according to daytime (1:00 to 6:00, 7:00 to 12:00, 13:00 to 18:00, and 19:00 to 24:00), weekday, month, and quarter. Meanwhile,the differences in various type of aortic dissection patient were also compared. Results: The patients were (51.4±12.0) years old,77.88% (873 cases)were male and 69.05% (774 cases) were type A aortic dissection.The peak period for the onset of the disease in a day was from 13:00 to 18:00 (401 cases. 35.77%),and disease onset was less frequent from 1:00 to 6:00 (196 cases, 17.48%).The peak weekday of disease onset was Monday (173 cases, 15.43%) , and disease onset was less frequent on Friday (153 cases, 13.65%) . The peak month of disease onset was January (135 cases, 12.04%), and disease onset was less frequent in July(54 cases, 4.82%). The peak season of disease onset was winter (349 cases, 31.13%), and disease onset was less frequent in summer (184 cases, 16.41%). Number of disease onset was similar between ≥65 years old and<65 years old groups, with or without hypertension groups, with or without Marfan syndrome groups at different periods of a day, each weekday, and seasons(all P>0.05). Conclusion: There are periodic changes in the onset of acute aortic dissection,which is higher in winter than in summer, higher in the afternoon than in the morning.
目的： 探讨主动脉夹层发病时间的特点。 方法： 纳入2010年1月1日至2016年12月31日在阜外医院治疗的来自河北省的所有急性主动脉夹层患者1 121例，对其临床资料进行回顾性分析。分析不同时段（包括1:00至6:00、7:00至12:00、13:00至18:00和19:00至24:00）、星期、月份和季节主动脉夹层的发病规律，并比较不同特征主动脉夹层患者在不同时间段、星期和季节的差异。 结果： 1 121例急性主动脉夹层患者的年龄为（51.4±12.0）岁，男性占77.88%（873例），A型主动脉夹层患者占69.05%（774例）。一天当中发病数量最多的时间段为13:00至18:00，共401例（35.77%）；发病数量最少的时间段为1:00至6:00，共196例（17.48%）。周一发病数量最多，共173例（15.43%）；周五发病数量最少，共153例（13.65%）。1月份发病数量最多，共135例（12.04%）；7月份发病数量最少，共54例（4.82%）。冬天发病数量最多，共349例（31.13%）；夏天发病数量最少，共184例（16.41%）。≥65岁与<65岁、高血压与无高血压、马方综合征与无马方综合征患者在不同时间段、星期和季节的发病数量差异均无统计学意义（P均>0.05）。 结论： 主动脉夹层发病时间具有冬季发病多而夏季发病少、下午发病多而上午发病少的规律。.
Keywords: Aortic diseases; Onset; Periodicity.