Short-term exposure of human sebocytes to 13-cis-retinoic acid induces acnegenic changes

Br J Dermatol. 2018 Nov;179(5):1201-1202. doi: 10.1111/bjd.16837. Epub 2018 Sep 11.
No abstract available

Publication types

  • Letter

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Apoptosis / drug effects
  • Arachidonate 5-Lipoxygenase / metabolism
  • Cell Line
  • Cell Proliferation / drug effects
  • Humans
  • Inflammation / chemically induced*
  • Isotretinoin / pharmacology*
  • Isotretinoin / therapeutic use
  • Leukotrienes / metabolism
  • Sebaceous Glands / cytology
  • Sebaceous Glands / drug effects*
  • Sebaceous Glands / metabolism
  • Sterol Regulatory Element Binding Protein 1 / metabolism
  • Time Factors

Substances

  • Leukotrienes
  • SREBF1 protein, human
  • Sterol Regulatory Element Binding Protein 1
  • Arachidonate 5-Lipoxygenase
  • ALOX5 protein, human
  • Isotretinoin