Abstract
We describe the rapid and ongoing emergence across multiple US cities of a new multidrug-resistant Escherichia coli clone-sequence type (ST) 1193-resistant to fluoroquinolones (100%), trimethoprim-sulfamethoxazole (55%), and tetracycline (53%). ST1193 is associated with younger adults (age <40 years) and currently comprises a quarter of fluoroquinolone-resistant clinical E. coli urine isolates.
Publication types
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Multicenter Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Communicable Diseases, Emerging / epidemiology*
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Communicable Diseases, Emerging / microbiology*
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Drug Resistance, Multiple, Bacterial*
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Escherichia coli / drug effects*
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Escherichia coli / genetics*
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Escherichia coli Infections / epidemiology
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Escherichia coli Infections / microbiology*
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Humans
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Population Surveillance
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Prevalence
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Retrospective Studies
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United States / epidemiology