Neoplasia and the Heart: Pathological Review of Effects With Clinical and Radiological Correlation

J Am Coll Cardiol. 2018 Jul 10;72(2):202-227. doi: 10.1016/j.jacc.2018.05.026.

Abstract

The intersection of oncological and cardiovascular diseases is an increasingly recognized phenomenon. This recognition has led to the emergence of cardio-oncology as a true subspecialty. This field is not simply limited to primary cardiac tumors or complications of chemotherapeutic medications. Rather, it also encompasses metastatic cardiovascular complications and secondary cardiovascular effects of the underlying neoplasia. This review will broadly cover primary and metastatic cardiac neoplasms, as well as secondary cardiovascular effects of extracardiac neoplasia (e.g., amyloidosis, carcinoid valvulopathy, and chemotherapeutic cardiotoxicities).

Keywords: masses; neoplasms; tumors.

Publication types

  • Review

MeSH terms

  • Carcinoid Heart Disease
  • Heart Neoplasms / diagnostic imaging
  • Heart Neoplasms / etiology
  • Heart Neoplasms / pathology*
  • Heart Neoplasms / therapy
  • Humans
  • Myocardium / pathology*
  • Neoplasm Metastasis