Abstract
Similar to ischemic preconditioning, high-intensity exercise has been shown to decrease infarct size following myocardial infarction. In this article, we review the literature on beneficial effects of exercise, exercise requirements for cardioprotection, common methods utilized in laboratories to study this phenomenon, and discuss possible mechanisms for exercise-mediated cardioprotection.
Keywords:
exercise; ischemic preconditioning; ischemic reperfusion; remote ischemic preconditioning.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Exercise Therapy*
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Humans
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Ischemic Preconditioning / methods*
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Ischemic Preconditioning, Myocardial
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Myocardial Infarction / mortality
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Myocardial Infarction / pathology
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Myocardial Infarction / physiopathology
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Myocardial Infarction / prevention & control*
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Myocardial Reperfusion Injury / mortality
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Myocardial Reperfusion Injury / pathology
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Myocardial Reperfusion Injury / physiopathology
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Myocardial Reperfusion Injury / prevention & control*
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Myocardium / metabolism
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Myocardium / pathology*
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Protective Factors
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Risk Factors
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Time Factors
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Treatment Outcome