Microbiome: Focus on Causation and Mechanism

Michael A Fischbach

doi:10.1016/j.cell.2018.07.038

Microbiome: Focus on Causation and Mechanism

Cell. 2018 Aug 9;174(4):785-790. doi: 10.1016/j.cell.2018.07.038.

Author

Michael A Fischbach¹

Affiliation

¹ Department of Bioengineering and ChEM-H, Stanford University and Chan Zuckerberg Biohub, Stanford, CA 94305, USA. Electronic address: fischbach@fischbachgroup.org.

Abstract

There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Bacterial Infections / diagnosis*
Bacterial Infections / microbiology
Bacterial Infections / prevention & control*
Humans
Microbiota*

Abstract

Publication types

MeSH terms

Grants and funding