Are Clinical Therapeutic Protein-Drug Interaction Studies Needed When Disease Modification Is Driving the Potential Interaction?

J Clin Pharmacol. 2018 Oct;58(10):1371-1372. doi: 10.1002/jcph.1290. Epub 2018 Aug 21.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents / pharmacokinetics*
  • Anti-Inflammatory Agents / therapeutic use*
  • Cytokines / genetics
  • Cytokines / metabolism
  • Drug Interactions*
  • Gene Expression Regulation / drug effects
  • Humans
  • Inflammation / drug therapy*
  • Proteins / metabolism*

Substances

  • Anti-Inflammatory Agents
  • Cytokines
  • Proteins